Preimplantation Genetic Diagnosis is a term used to describe a process used to detect certain abnormal chromosomes or genes in human embryos.

Currently, PGD is available to be done with In-Vitro Fertilization.

PGD can analyze the following chromosomes for aneuploidy (abnormal number of chromosomes). The most commonly analyzed chromosomes are: 13,15,16,17,18,21,22,X and Y.

PGD can analyze embryos for specific gene defects or diseases. The most common gene defects analyzed are: Cystic Fibrosis, Sickle Cell Anemia, and Duchene Muscular Dystrophy.

PGD can be used to identify specific chromosomal translocations, i.e. when a parent carries a chromosome translocation.

PGD can be used to identify additional specific chromosome abnormalities or specific single gene defects.

Patients who are considering using PGD will be scheduled for counseling with a genetic counselor.

PGD is offered to improve pregnancy outcomes for parents with known genetic risk factors, family history or inherited disease or sex-linked diseases.

PGD is also offered to patients with recurrent implantation failure and maternal age more than 38 years old.